Я использую System.IO.Abstractions пакет NuGet.

Этот веб-сайт имеет хороший пример, показывающий Вам, как использовать инжекцию для тестирования. http://dontcodetired.com/blog/post/Unit-Testing-C-File-Access-Code-with-SystemIOAbstractions

Вот копия кода, скопированного с веб-сайта.

using System.IO;
using System.IO.Abstractions;

namespace ConsoleApp1
{
    public class FileProcessorTestable
    {
        private readonly IFileSystem _fileSystem;

        public FileProcessorTestable() : this (new FileSystem()) {}

        public FileProcessorTestable(IFileSystem fileSystem)
        {
            _fileSystem = fileSystem;
        }

        public void ConvertFirstLineToUpper(string inputFilePath)
        {
            string outputFilePath = Path.ChangeExtension(inputFilePath, ".out.txt");

            using (StreamReader inputReader = _fileSystem.File.OpenText(inputFilePath))
            using (StreamWriter outputWriter = _fileSystem.File.CreateText(outputFilePath))
            {
                bool isFirstLine = true;

                while (!inputReader.EndOfStream)
                {
                    string line = inputReader.ReadLine();

                    if (isFirstLine)
                    {
                        line = line.ToUpperInvariant();
                        isFirstLine = false;
                    }

                    outputWriter.WriteLine(line);
                }
            }
        }
    }
}





using System.IO.Abstractions.TestingHelpers;
using Xunit;

namespace XUnitTestProject1
{
    public class FileProcessorTestableShould
    {
        [Fact]
        public void ConvertFirstLine()
        {
            var mockFileSystem = new MockFileSystem();

            var mockInputFile = new MockFileData("line1\nline2\nline3");

            mockFileSystem.AddFile(@"C:\temp\in.txt", mockInputFile);

            var sut = new FileProcessorTestable(mockFileSystem);
            sut.ConvertFirstLineToUpper(@"C:\temp\in.txt");

            MockFileData mockOutputFile = mockFileSystem.GetFile(@"C:\temp\in.out.txt");

            string[] outputLines = mockOutputFile.TextContents.SplitLines();

            Assert.Equal("LINE1", outputLines[0]);
            Assert.Equal("line2", outputLines[1]);
            Assert.Equal("line3", outputLines[2]);
        }
    }
}